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阻害剤

天然化合物

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カタログ番号	製品名	別名
T37839	20-hydroxy Prostaglandin E2	20-hydroxy Prostaglandin E2
	20-hydroxy Prostaglandin E2 (20-hydroxy PGE2) is a product of cytochrome P450 metabolism of PGE2 . ω-Oxidation at C-20 followed by β-oxidation and the loss of up to four carbons from the lower side chain is a prominent m...
T37322	Steryl Glucosides
	Steryl glucosides are neutral glycolipids commonly found in plant cell membranes and vegetable oils that contain a glucose moiety conjugated to a sterol lipid. They function as glucose donors in the biosynthesis of gluco...
T37257	13,14-dihydro-15-keto Prostaglandin D1	13,14-dihydro-15-keto Prostaglandin D1
	Prostaglandin D1 (PGD1) is the theoretical D-series metabolite of dihomo-γ-linolenic acid (DGLA), but to date it has not been isolated as a natural product. It is an inhibitor of ADP-induced platelet aggregation in human...
T37716	Galactosylcerebrosides (hydroxy)
	Galactosylcerebrosides are glycosphingolipids that contain a galactose attached to a ceramide acylated with a hydroxy or non-hydroxy fatty acid. They are metabolic precursors to sulfatides , found primarily in nerve tiss...
T37717	Galactosylcerebrosides (non-hydroxy)
	Galactosylcerebrosides are glycosphingolipids that contain a galactose attached to a ceramide acylated with a hydroxy or non-hydroxy fatty acid. They are metabolic precursors to sulfatides , found primarily in nerve tiss...
TMIH-0181	Demethoxy Curcumin-d4
	Demethoxy Curcumin-d4 is a deuterated compound of Demethoxy Curcumin. Demethoxy Curcumin has a CAS number of 22608-11-3. 1. Demethoxycurcumin has antioxidant activity. 2. Demethoxycurcumin has anti-inflammatory activity....
T37631	Tetranor-12(S)-HETE
	12(S)-HETE is a product of arachidonic acid metabolism through the 12-lipoxygenase pathway. It is primarily found in platelets, leukocytes, and to a lesser extent in smooth muscle cells. It enhances tumor cell adhesion t...
T83765	Dendrogenin A	DDA
	Dendrogenin A (DDA) is a compound acting as a selective liver X receptor (LXR) modulator, cholesterol epoxide hydrolase inhibitor (Ki = 120 nM), and a metabolic product of cholesterol, originating from 5,6α-epoxy cholest...
T35524	(1S)-Calcitriol
	(1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3), a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3), exerts potent actions through vitamin D receptor (VDR) activation, including the inhibition of keratin...

Compounds

20-hydroxy Prostaglandin E2

T37839

Synonym: 20-hydroxy Prostaglandin E2

13,14-dihydro-15-keto Prostaglandin D1

T37257

Synonym: 13,14-dihydro-15-keto Prostaglandin D1

Target:

Galactosylcerebrosides (hydroxy)

T37716

Synonym:

Target:

Galactosylcerebrosides (non-hydroxy)

T37717

Synonym:

Target:

Demethoxy Curcumin-d4

カタログ番号	製品名	別名	ターゲット
T1688	Pregnanediol	5Beta-Pregnane-3Alpha,20alpha-Diol,Pregnandiol	Estrogen/progestogen Receptor , Endogenous Metabolite
	Pregnanediol (5Beta-Pregnane-3Alpha,20alpha-Diol) is an inactive metabolite of PROGESTERONE by reduction at C5, C3, and C20 position. Pregnanediol(5Beta-Pregnane-3Alpha,20alpha-Diol) has two hydroxyl groups, at 3-alpha a...		Estrogen/progestogen Receptor , Endogenous Metabolite
T0529	Dulcite	Galactitol,Dulcitol,Euonymit,NSC 1944,D-Galactitol,Melampyrit	Endogenous Metabolite
	Dulcite (D-Galactitol) is a sugar alcohol that is a metabolic breakdown product of galactose.		Endogenous Metabolite
T5788	XYLOBIOSE		IL Receptor , TNF
	XYLOBIOSE ia a natural product,and exhibited therapeutic potential for treating obesity which involved suppression of fat deposition and obesity-related metabolic disorders.		IL Receptor , TNF
T5268	D-Arabitol	D-Lyxitol	Others , Endogenous Metabolite
	D-Arabitol (D-Lyxitol) is a polyol. Polyols are sugar alcohols linked to the pentose phosphate pathway (PPP). Polyols occur in body fluids. It is thought that D-arabitol is a metabolic end-product in humans.		Others , Endogenous Metabolite
T6S1683	Demethoxycurcumin	Curcumin II,Desmethoxycurcumin,Monodemethoxycurcumin	Apoptosis , Antioxidant , Antibacterial , Autophagy
	1. Demethoxycurcumin (Desmethoxycurcumin) has antioxidant activity. 2. Demethoxycurcumin has anti-inflammatory activity. 3. Demethoxycurcumin has anti-proliferative activity. 4. Demethoxycurcumin has anti-acanthamoebic e...		Apoptosis , Antioxidant , Antibacterial , Autophagy
T4734	Suberic acid	Octanedioic acid,1,8-Octanedioic acid	Others , Endogenous Metabolite
	Suberic acid (1,8-Octanedioic acid) is present in the urine of patients with fatty acid oxidation disorders. A metabolic breakdown product derived from oleic acid. Elevated levels of this unstaruated dicarboxylic acid ar...		Others , Endogenous Metabolite
T8274	3-Methyl-L-histidine		Endogenous Metabolite
	3-Methylhistidine belongs to the class of organic compounds known as histidine and derivatives. Histidine and derivatives are compounds containing cysteine or a derivative thereof resulting from reaction of cysteine at t...		Endogenous Metabolite
T78471	α,α-Trehalose 6-phosphate potassium	Tre6P potassium	Endogenous Metabolite
	α,α-Trehalose 6-phosphate (Tre6P) potassium is an intrinsic 6-phosphate derivative of α,α′-trehalose and acts as an intermediary metabolite. It undergoes enzymatic conversion to the final metabolic product, α,α′-trehalos...		Endogenous Metabolite
TN5530	Volkensiflavone	Talbotaflavone	Others
	Volkensiflavone (Talbotaflavone) is a natural product found in astragalus and garcinia. It has the function of plant metabolite, is a secondary metabolic product. Volkensiflavone is a biflavonoid belonging to the hydroxy...		Others
TN3779	De-O-methyllasiodiplodin		IL Receptor , TNF , ROS , Antifection
	De-O-methyllasiodiplodin exhibits radical scavenging, moderate antibacterial, and potential anti-inflammatory effects, it shows moderate suppression effects on induced NO production. De-O-methyllasiodiplodin effectively ...		IL Receptor , TNF , ROS , Antifection
T36563	(E)-Guggulsterone
	Bile acids are essential for solubilization and transport of dietary lipids, are the major products of cholesterol catabolism, and are physiological ligands for farnesoid X receptor (FXR), a nuclear receptor that regulat...

天然物製品

Pregnanediol

T1688

Synonym: 5Beta-Pregnane-3Alpha,20alpha-Diol,Pregnandiol

Target: Estrogen/progestogen Receptor, Endogenous Metabolite

Dulcite

T0529

Synonym: Galactitol,Dulcitol,Euonymit,NSC 1944,D-Galactitol,Melampyrit

Target: Endogenous Metabolite

XYLOBIOSE

T5788

Synonym:

Target: IL Receptor, TNF

D-Arabitol

T5268

Synonym: D-Lyxitol

Target: Others, Endogenous Metabolite

Demethoxycurcumin

T6S1683

Synonym: Curcumin II,Desmethoxycurcumin,Monodemethoxycurcumin

Target: Apoptosis, Antioxidant, Antibacterial, Autophagy

Suberic acid

T4734

Synonym: Octanedioic acid,1,8-Octanedioic acid

Target: Others, Endogenous Metabolite

3-Methyl-L-histidine

T8274

Synonym:

Target: Endogenous Metabolite

α,α-Trehalose 6-phosphate potassium

T78471

Synonym: Tre6P potassium

Target: Endogenous Metabolite

Volkensiflavone

TN5530

Synonym: Talbotaflavone

Target: Others

De-O-methyllasiodiplodin

TN3779

Synonym:

Target: IL Receptor, TNF, ROS, Antifection

カタログ番号	製品名
L6600	Anti-Gastroenteritis Natural Product Library		219 compounds
	A unique collection of 219 natural products related to gastroenteritis for high throughput screening (HTS) and high content screening (HCS);

ライブラリー

Anti-Gastroenteritis Natural Product Library

L6600

Compounds: 219